What exactly is NMN?
NMN is short for nicotinamide mononucleotide, a naturally occurring molecule present in all species. About the molecular level, it’s a ribonucleotide, a fundamental structural unit in the nucleic acid RNA. It includes a nicotinamide group, a ribose, and a phosphate group.
NMN is often a precursor of nicotinamide adenine dinucleotide (NAD+), a molecule that could be beneficial in reducing some elements of aging. NAD+ serves many critical functions in your cells, including electron transport, cell signaling, and DNA repair.
Accumulating evidence shows that as we age, our numbers of NAD+ decline, increasing our likelihood of age-related diseases.
This is where the NAD+ precursor NMN will come in. Some researchers think that as we can restore that lost NAD+, we’re able to not merely slow down aging and also delay various age-related diseases. Whether or not restoring NAD+ metabolism in humans will decelerate aging or support healthy longevity remains to be an unanswered question, although the animal details are promising.
What foods contain NMN?
NMN is found naturally in foods for example avocado, broccoli, cabbage, cucumber, and edamame. Here’s how much NMN is situated in some common foods.
While such foods are an excellent source of nutrition, dietary NMN supplements can be found. These supplements typically come in doses which is between 100 – 500 mg, although an ideal dose has to be determined in people.
Fasting and caloric restriction also may actually increase NAD+ levels and increase the activity of sirtuins, aka the longevity genes. It is suggested that their activity relies upon the use of NAD+. In mice, fasting boosted NAD+ levels and sirtuin activity, and yes it seems to decrease aging.
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