SINCE Wwii, medical science has progressed to a stage where competitive medications are available to treat the identical ailment in several people. This isn’t just about brands (that is a trade issue) but generic drugs (that is a scientific issue). In this report, we shall glance at the various factors that decide picking a a certain drug.
Safety: The next sub-criteria has to be considered beneath the criterion of safety:
* Acute therapeutic index: When the patient’s condition is acute, how effective can be a particular drug even when it’s got certain side-effects providing the acuteness of the condition is lowered? Example: narcotic pain-killers are incredible in healing pain but have the potential side-effect of addiction.
* Long-term safety: medicationdirectory.com could be safe in short-term treatment, but how safe it’s in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but sometimes have undesirable effects in the event of prolonged use.
* Drug-drug interaction risk: Medicine is chemicals, and a lot of chemicals answer develop a different chemical, that have an effect that could harm the individual or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to produce a new condition that warrants separate treatment.
Drug-drug interaction risk is of two types:
· Pharmacokinetic: In this type of drug-drug interaction, two drugs, independent of the other, have certain effects using one or even more body processes (e.g., metabolism) that affects the performance of the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the action of a liver enzyme that Lexapro (escitalopram) depends on for its metabolism. This leads to a boost in the side-effects of Lexapro.
· Pharmacodynamic: Here, a couple of drugs actually generate the same effect on the identical organ, thus increasing the total, added effect. Example: Lexapro has certain side-effects for example drowsiness and fatigue. Darvocet-N also acts similarly on the brain. Thus, the side-effects of both prescription medication is more serious.
Tolerability: A medicine could be effective however, not tolerable by all patients. Example: Allergies to certain drugs in most people. Short-term and long-term tolerability should be looked at. Efficacy: A medicine is not equally effective in all patients. As an example, some patients with depression or panic attacks experience reduced escitalopram, but there are several who don’t, who therefore should be prescribed another anti-depressant. The pace of beginning of therapeutic action is an important the answer to be considered too.
Cost: Cost does not always mean the price tag on acquisition of a particular medicine alone. It should also cover the price tag on treating a complication that could arise by using another drug. Example: Within a individual who insists on taking alcohol yet must be treated for depression is often administered an SSRI drug since these drugs don’t potentiate the end results of alcohol, whereas another band of anti-depressants (for example tricyclics) can cause a brand new overuse injury in such patients, which may require a various and expensive treatment. Therefore, it’s easier to prescribe the more costly escitalopram rather than a cheaper tricyclic in these patients.
Simple treatment: The best mode of administration is preferred. When there is an option between a shot and oral administration, the second is preferred when the efficacy of both modes is comparable. Or, local application is preferred to the oral route where possible; e.g., antibiotic treating eye infections. Dosage and frequency of administration too are a key factor to choose simple treatment.
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